Workshop: Biology of Signaling in the
Cardiovascular System
September 11-14, 2008 - Cape Codder Resort, Hyannis,
Massachusetts
Organizers: Timothy Hla, University of Connecticut
and
Michael Simons, Dartmouth Medical School
Preliminary Program:
|
1. |
The vascular cell surface-I | ||
| Luisa Iruela-Arispe- University of California, Los Angeles | |||
| Location, location, location in VEGF signaling | |||
|
|
Robert Friesel, Maine Medical Center Research Institute | ||
| Feedback inhibition of receptor tyrosine kinase signaling in the endothelial cell | |||
|
|
David Cheresh, University of California, San Diego | ||
| Role of Raf in vascular development and angiogenesis | |||
|
|
Helmut Augustin, University of Heidelberg - German Cancer Research Center | ||
| Ang-2 and Tie1 as dynamic regulators of constitutive Ang-1/Tie2 signaling in the vascular system | |||
|
2. |
The vascular cell surface-II | ||
|
|
J. Silvio Gutkind, National Institute of Dental and Craniofacial Research | ||
| A G Protein-coupled receptor and VE-cadherin cross-talk: A role in vascular permeability and tumor induced-angiogenesis? | |||
| Nigel Mackman, Scripps Research Institute | |||
| Regulation of coagulation by endothelial cell receptors | |||
| Tatiana Byzova, Lerner Research Institute, Cleveland Clinic Foundation | |||
| Integrin and growth factor alliance in angiogenesis | |||
|
|
Christiana Rurhberg, University College London | ||
| Understanding neuropilin function in vascular development | |||
|
3. |
Phosphorylation cascades | ||
|
|
Dario Alessi, University of Dundee | ||
| Regulation and function of the LKB1 kinase | |||
|
|
John Blenis, Harvard Medical School | ||
| mTORC1 signaling | |||
|
|
George Yancopoulos, Regeneron Pharmaceuticals | ||
| VEGF regulation of angiogenesis: The Delta Paradox | |||
|
|
Kenneth Walsh, Boston University | ||
| Akt, mTOR and organ growth | |||
|
4. |
Intracellular transducers and Nodes | ||
|
|
Jonathan Stamler, Duke University Medical Center | ||
| Protein S-nitrosyltion in the cardiovascular system | |||
|
|
William C. Sessa, Yale University School of Medicine | ||
| NO-based signal transduction | |||
|
|
Sankar Ghosh, Yale University School of Medicine | ||
| Regulation of immune and inflammatory responses by NF-kB | |||
|
|
Kimberly Dodge-Kafka, University of Connecticut Health Center | ||
| The molecular architecture of camp microdomains | |||
|
5. |
Signaling in development | ||
| David Ornitz, Washington University, St. Louis | |||
| Growth factor signaling pathways that regulate myocardial development and coronary vasculogenesis: From developmental biology to therapeutic implications | |||
| Jan K. Kitajewski, Columbia University | |||
| Notch and VEGF pathways interact to regulate angiogenesis | |||
| Anne Eichmann, Collège de France, INSERM U36 | |||
| Neural guidance receptors in vascular patterning | |||
| Michelle D. Tallquist, UT Southwestern Medical Center | |||
| Novel functions for PDGF receptor signaling in blood vessel development | |||
|
6. |
Post-translational signals | ||
|
|
Joe G.N. Garcia, University of Chicago | ||
| Receptor signaling to the endothelial cytoskeleton | |||
| Martin A. Schwartz, University of Virginia | |||
| Integrins, ECM and atherosclerosis | |||
|
|
Stephan Offermans, University of Heidelberg | ||
| G-protein mediated signaling in vascular physiology and pathophysiology | |||
| 7. | Extracellular stimuli | ||
| Elena Tzima, University of North Carolina, Chapel Hill | |||
| Shear stress: atheroprotection vs. atherogenesis | |||
| Gregg L. Semenza, Johns Hopkins University | |||
| Regulation of angiogenesis and arteriogenesis by hypoxia-inducible factor 1 | |||
| Mark H. Ginsberg, University of California, San Diego | |||
| Regulation of vascular integrins | |||
|
|
Horace M. Delisser, University of Pennsylvania | ||
| PECAM-1 as a Facilitator of Endothelial Cell Motility | |||
|
8. |
System integration and quantitative approaches | ||
|
|
Leslie M. Loew, University of Connecticut Health Center | ||
| Modeling cell signaling with virtual cell | |||
|
|
Jan Schnitzer, Sidney Kimmel Cancer Center | ||
| Quantitative proteomic and systems analysis of endothelial cell surfaces in vivo: Integrating signaling and trafficking via caveolae | |||
|
|
Charles Serhan, Brigham & Women's Hospital, Harvard Medical School | ||
| Lipid mediator lipidomics-informatics and inflammatory pathophysiology | |||
|
|
Sudhansu K. Dey, Vanderbilt University Medical Center | ||
| Hormonal regulation uterine vascular permeability and angiogenesis during pregnancy | |||
