Workshop: Biology of Signaling in the
Cardiovascular System
September 11-14, 2008 - Cape Codder Resort, Hyannis,
Massachusetts
Organizers: Timothy Hla, University of Connecticut
and
Michael Simons, Dartmouth Medical School
Preliminary Program:
| Thursday, September 11 | |||
|
7:00 pm |
Welcome and Introductions | ||
| Signaling in development | |||
| 7:10 pm | David Ornitz, Washington University, St. Louis | ||
| Growth factor signaling pathways that regulate myocardial development and coronary vasculogenesis: From developmental biology to therapeutic implications | |||
| 7:40 pm | Jan K. Kitajewski, Columbia University | ||
| Notch and VEGF pathways interact to regulate angiogenesis | |||
| 8:10 pm | Anne Eichmann, Collège de France, INSERM U36 | ||
| Neural guidance receptors in vascular patterning | |||
| 8:40 pm | Michelle D. Tallquist, UT Southwestern Medical Center | ||
| Novel functions for PDGF receptor signaling in blood vessel development | |||
| Welcome Reception | |||
|
9:15-10:30pm |
|||
| Friday, September 12 | |||
| 7:00 am | Breakfast | ||
| The vascular cell surface-I | |||
| 8:00 am | Luisa Iruela-Arispe- University of California, Los Angeles | ||
| Location, location, location in VEGF signaling | |||
| 8:30 am |
|
Robert Friesel, Maine Medical Center Research Institute | |
| Feedback inhibition of receptor tyrosine kinase signaling in the endothelial cell | |||
| 9:00 am |
|
David Cheresh, University of California, San Diego | |
| Role of Raf in vascular development and angiogenesis | |||
| 9:30 am | Coffee Break | ||
| 10:00 am |
|
Helmut Augustin, University of Heidelberg - German Cancer Research Center | |
| Ang-2 and Tie1 as dynamic regulators of constitutive Ang-1/Tie2 signaling in the vascular system | |||
| 10:30 am | Two oral abstract presentations TBD | ||
| 11:00am | Visit the exhibits and posters | ||
| 12:00 pm | Lunch | ||
| The vascular cell surface-II | |||
|
1:00 pm |
|
J. Silvio Gutkind, National Institute of Dental and Craniofacial Research | |
| A G Protein-coupled receptor and VE-cadherin cross-talk: A role in vascular permeability and tumor induced-angiogenesis? | |||
|
1:30 pm |
Tatiana Byzova, Lerner Research Institute, Cleveland Clinic Foundation | ||
| Integrin and growth factor alliance in angiogenesis | |||
|
2:00 pm |
Two oral abstract presentations TBD | ||
|
2:30 pm |
Coffee Break | ||
| 3:00 pm |
|
Christiana Rurhberg, University College London | |
| Understanding neuropilin function in vascular development | |||
| 4:00 pm | Poster sessions and exhibits | ||
| 6:00 pm | Dinner on your own | ||
|
Intracellular transducers and Nodes |
|||
| 8:00 pm |
|
Jonathan Stamler, Duke University Medical Center | |
| Protein S-nitrosyltion in the cardiovascular system | |||
| 8:30 pm |
|
William C. Sessa, Yale University School of Medicine | |
| NO-based signal transduction | |||
| 9:00 pm |
|
Asrar Malik, University of Illinois at Chicago | |
| eNOS/caveolin-1 interactions | |||
| 9:30 pm |
|
Kimberly Dodge-Kafka, University of Connecticut Health Center | |
| The molecular architecture of camp microdomains | |||
| Saturday, September 13 | |||
| 7:00 am | Breakfast | ||
| Extracellular stimuli | |||
| 8:00 am | Elena Tzima, University of North Carolina, Chapel Hill | ||
| Shear stress: atheroprotection vs. atherogenesis | |||
| 8:30 am | Two oral abstract presentations TBD | ||
| 9:00 am | Mark H. Ginsberg, University of California, San Diego | ||
| Regulation of vascular integrins | |||
| 9:30 am | Coffee Break | ||
| 10:00 am |
|
Gregg L. Semenza, Johns Hopkins University | |
| Regulation of angiogenesis and arteriogenesis by hypoxia-inducible factor 1 | |||
| 10:30 am | Two oral abstract presentations TBD | ||
| 11:00am | Visit the exhibits and posters | ||
| 12:00 pm | Lunch | ||
| Phosphorylation cascades | |||
| 1:00 pm |
|
John Blenis, Harvard Medical School | |
| mTORC1 signaling | |||
| 1:30 pm | Two oral abstract presentations TBD | ||
| 2:00 pm |
|
George Yancopoulos, Regeneron Pharmaceuticals | |
| VEGF regulation of angiogenesis: The Delta Paradox | |||
| 3:30 pm |
|
Kenneth Walsh, Boston University | |
| Akt, mTOR and organ growth | |||
| 4:00 pm | Poster sessions and exhibits | ||
| 6:00 pm | Dinner on your own | ||
|
Post-translational signals |
|||
| 8:00 pm |
|
Joe G.N. Garcia, University of Chicago | |
| Receptor signaling to the endothelial cytoskeleton | |||
| 8:30 pm | Martin A. Schwartz, University of Virginia | ||
| Integrins, ECM and atherosclerosis | |||
| 9:00 pm |
|
Stefan Offermans, University of Heidelberg | |
| G-protein mediated signaling in vascular physiology and pathophysiology | |||
| 9:30 pm |
|
Sankar Ghosh, Yale University School of Medicine | |
| Regulation of immune and inflammatory responses by NF-kB | |||
| Sunday, September 14 | |||
| 7:00 am | Breakfast | ||
| Signaling and Vascular Disease | |||
| 8:00 am |
|
Horace M. Delisser, University of Pennsylvania | |
| PECAM-1 as a Facilitator of Endothelial Cell Motility | |||
|
8:30 am |
Two oral abstract presentations TBD | ||
|
System integration and quantitative approaches |
|||
| 9:00 am |
|
Leslie M. Loew, University of Connecticut Health Center | |
| Modeling cell signaling with virtual cell | |||
| 9:30 am |
|
Jan Schnitzer, Sidney Kimmel Cancer Center | |
| Quantitative proteomic and systems analysis of endothelial cell surfaces in vivo: Integrating signaling and trafficking via caveolae | |||
| 10:00 am | Coffee Break | ||
| 10:30 am |
|
Charles Serhan, Brigham & Women's Hospital, Harvard Medical School | |
| Lipid mediator lipidomics-informatics and inflammatory pathophysiology | |||
| 11:00 am |
|
Sudhansu K. Dey, Cincinnati Children's Hospital Medical Center | |
| Hormonal regulation uterine vascular permeability and angiogenesis during pregnancy | |||
| 11:30 am | Two to four oral abstract presentations TBD | ||
| 1:00 pm | Conference concludes | ||
