Vascular Biology 2008 Preliminary Program

April 5-9, 2008 - San Diego, CA

this meeting is held in conjunction with the American Society for Investigative Pathology
at Experimental Biology 2008


Mini-symposium: Angiogenesis and Vascular Differentiation
Chairs: Heidi Stuhlmann, Weill Medical College and Joanne Chan, Children's Hospital, Boston

Saturday, April 5, 2008 – 8:30-11:30am, Room 17A

Meet the Professor Luncheon
Sponsored by Springer - publisher of Angiogenesis
Saturday, April 5, 2008 - 12:00-1:45pm
San Diego Marriott Hotel and Marina - Sea View Room

Blood Vessel Club:  Stem/progenitor cells - Contributions to blood vessel assembly and repair
(co-sponsored with the American Society for Investigative Pathology)
        The format will consist of two invited speakers and short talk “blitzes”
Saturday, April 5, 2008 – 2:00-4:00pm, Room 15B
Chair: David Milstone, Harvard Medical School and Co-chair: Joyce Bischoff, Children's Hospital, Boston
Speakers: Vivek Mittal, Cold Spring Harbor Laboratory
              Juan Melero-Martin, Children's Hospital Boston
              Dmitry O. Traktuev, Indiana University

Welcome Reception/Highlighting Trainee Research
Saturday, April 5, 2008 - 6:15-7:30 pm, Room 15B

 

Neurovascular connections/interactions
(co-sponsored with the American Association of Neuropathologists
)
Sunday, April 6, 2008 – 2:00-5:00pm, Room 15A
Chairs: Jeffrey A. Golden,  Children's Hospital of Pennsylvania
and Christiana Ruhrberg, University College London, UK
Speakers:
Peter Carmeliet, University of Leuven, Belgium
   The Neuro-Vascular link in health and disease: From genetic insights to therapeutic perspectives
T. Makita, The Johns Hopkins University
   Endothelins are vascular-derived axonal guidance cues for developing sympathetic neurons
J. Long, Yale University
   Determining the molecular mechanisms of vascular sympathetic innervation
Chenghua Gu, Harvard Medical School
   The molecular mechanisms of axon and vascular guidance
Christiana Ruhrberg, University College London
   VEGF in the nervous system: Co-patterning of blood vessels, neurons and glia
Joseph H. McCarty, MD Anderson Cancer Center
   Integrin-mediated adhesion and signaling in the neurovascular niche
David Zagzag, New York University
   Hypoxia-induced angiogenesis and brain invasion in gliomas
 

--Of interest - AAA's related session (Tuesday, April 8. 2:30pm - Room 7A):
        Crosstalk and codependence between neural and vascular systems
           
Chair: Nicole Ward, Case Western Reserve University
                Yosuke Mukoyama, National Institutes of Health
                    Control of Blood Vessel Fate & Branching Pattern by Nerve-Derived Signals
                Anne Eichmann, Collège de France
                    Neuronal Molecules Involved in Blood Vessel Branching
                Adam Puche, University of Maryland
                    Migrating the Adult Brain: Vascular & ECM Mediated?
                S. Thomas Carmichael, Geffen School of Medicine at UCLA
                    A Neurovascular Niche for Neurogenesis after Stroke
 

Minisymposium: Modulators of Atherosclerosis and Other Vascular Diseases

Chairs: Craig A. Simmons, University of Toronto and Cecilia M. Giachelli, University of Washington

Sunday, April 6, 2008 – 2:00-5:00pm, 15B


Of special note:
   
Michael A. Gimbrone, Jr., Brigham & Women's Hospital/Harvard Medical School
        will give the ASIP Rous-Whipple Award Lecture:

            Vascular Endothelium in the Post Genomic Era: New Insights into its Pathobiology
           
Sunday, April 6, 5:00pm, Room 16A
 

Vascular Cell Dysfunction in Disease
Chair: Tim Hla, University of Connecticut
Monday April 7, 2008  - 8:30 - 11:30 am, Room 15A
Speakers:
Joyce Bischoff, Children's Hospital, Boston
    Hemangioma, an endothelial tumor of infancy, arises from a multipotential stem cell

Gabriele Bergers, University of California, San Francisco
    Vascular progenitor cells in tumors

Sung O. Park, University of Florida
    ALK1 signaling plays a pivotal role in regulation of genes involved in angiogenesis and vascular tone:
    Implication on the pathogenetic mechanism for hereditary hemorrhagic telangiectasia 2 (HHT2)

Susan Quaggin, University of Toronto
    Podocyte-endothelial interactions and angiogenic factors in glomerular development and disease.
Louisa Villeneuve, Beckman Research Institute of City of Hope
    Novel epigenetic mechanisms involved in enhanced inflammatory gene expression in vascular
    smooth muscle cells derived from diabetic db/db mice and relation to diabetic memory

Mukesh Jain, Case Cardiovascular Research Institute, Cleveland, OH
    Kruppel-like factors in vascular pathophysiology
 

Minisymposium: Vascular Cell Membrane Biology

Chairs: Tara L. Sander, Medical College of Wisconsin and Radu V. Stan, Dartmouth Medical School

Monday, April 7, 2008 – 2:00-5:00pm, Room 17A 


Earl P. Benditt Award Presentation and Lecture:
 
Shaun R. Coughlin, University of California, San Francisco
Monday, April 7 at 5pm - Room 17B
    Protease-activated receptors in vascular biology

The Immune System in Vascular Diseases
Chair: Klaus Ley, La Jolla Institute for Allergy and Immunology
Tuesday April 8, 2008 – 8:30-11:30am, Room 17A
Speakers:
Klaus Ley, La Jolla Institute for Allergy and Immunology
    Chemokine receptors and adhesion molecules in immune cell trafficking into atherosclerotic arteries
Arjan Griffioen – University Hospital Maastricht, The Netherlands
    Angiogenesis inhibition promotes an anti-tumor immune response.
J. Boyle, Imperial College, London, United Kingdom
  Atherosclerotic intralesional haemorrhage moulds monocyte differentiation into a macrophage
  antioxidant phenotype bearing the hemoglobin scavenger receptor CD163
Z. Mallat, Center for Cardiovascular Research, INSERM, Paris, France
    T cell regulation in atherosclerosis and related vascular diseases
Joseph Witztum, University of California, San Diego
    Oxidation-specific epitopes are a major target of innate natural antibodies
M. Lewis, Imperial College, London, United Kingdom
  Hierarchical contributions of IgM and complement C1q in protection against murine atherosclerosis

NAVBO Membership Business Meeting
Tuesday, April 8, 2008 - 11:45am-12:30pm, Room 17A

Minisymposium: Molecular Regulation in Vascular Cells

Chairs: Levon Khachigian, University of New South Wales and Anna M. Randi, Imperial College London

Tuesday, April 8, 2008 – 2:00-5:00pm, Room 17A

Molecular engines that regulate epithelial and endothelial junctions
(co-sponsored with the American Society for Investigative Pathology)
Tuesday, April 8, 2008 – 2:00-5:00pm, Room 16B
Chairs: William Muller, Northwestern University and Andrei Ivanov, Emory University
Speakers:
Albert B. Reynolds, Department of Cancer Biology, Vanderbilt University.
    Role of p120-catenin in regulation of epithelial junctions.
Keith Burridge, UNC Chapel Hill
    Regulation of endothelial permeability by small GTPases.
Tony Pawson, Samuel Lunenfeld Research Institute. Mount Sinai Hospital, Toronto.
    Rich-1 and Angiomotin as novel regulators of epithelial tight junctions.
Fitzroy Curry, University of California, Davis
    Determinants of microvascular permeability in vivo
.

Poster Sessions will be held Sunday through Tuesday
(late breaking abstracts will be presented on Wednesday)

Angiogenesis and Vascular Differentiation
Atherosclerosis and Other Vascular Diseases
Molecular Regulation in Vascular Cells
Thrombosis and Hemostasis
Vascular Extracellular Matrix, Proteases and Tissue Engineering
Vascular Permeability and Reactivity

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