Vasculata 2008
University of Washington, Seattle
August 4-7, 2008
Organizers: Stephen M. Schwartz with David Dichek and Charles Murry
Preliminary Program
VASCULATA 2008 will be held in Seattle, August 4-7, 2008. Student registration is $50. For graduate and postdoc NAVBO members, registration will be $125 while non members will be $200. All others, faculty, senior researchers etc. registration is $300. Students registered at the University will be expected to register for Path 511 and may take the course as credit/non-credit, free of other charges. All lectures and breakouts will be in the first floor auditorium, UW SLU Campus, Brotman Building, 815 Mercer Street, Seattle, WA 98109-4714.
COURSE STRUCTURE: Day one is intended to be a rapid overview of the major issues in Vascular Biology. Each of the lectures on following days is intended to present a central research problem in vascular biology. Following the morning and afternoon lectures, we will hold breakout sessions where students will meet with three faculty members for open discussion of topics arising from the lectures.
August 4 - Basic Vascular Biology, Starting at the Membrane
Lectures: 8:30 am 9:20 am - The Major Vascular Diseases in 50 Minutes - Stephen Schwartz, University of Washington
9:30 am 10:20 am - Developmental Biology - Mark Majesky, University of North Carolina, Chapel Hill
10:30 am 11:20 am - Lineage tracing and the question of circulating stem cells - Daniel Bowen-Pope, University of Washington
Breakout: 11:30 am 12:15 pm - Vascular Injury Francis Kim, Atis Muehlenbachs; Alex Clowes
Lectures: 1:30 pm - 2:20 pm - Smooth Muscle Mass Gary Gibbons, Morehouse School of Medicine
2:30 pm - 3:20 pm - The Endothelial Membrane Tim Hla, University of Connecticut
3:30 pm - 4:20 pm - Proteomics: The Topside of the Endothelium - Jan Schnitzer, Sidney Kimmel Cancer Center
Breakout: 4:30 pm 5:20 pm - Membrane Biology Fernando Santana, Debra Schwinn, Jan Schnitzer
Evening: Brief Presentations of Training Programs Represented at VASCULATA followed by reception and Trainee Posters
August 5 - The Vessel Wall and Inflammation
Lectures: 8:30 am 9:20 am - Inflammation: Is the vessel wall part of the immune system? Keith Elkon, University of Washington
9:30 am 10:20 am - Inflammation: Do platelets and monocytes interact in the circulation? - Josι Lopez, Puget Sound Blood Center
10:30 am 11:20 am - Inflammation: Is scleroderma a systemic vascular disease? Jo Fleming, University of Washington
Breakout: 11:30 am 12:15 pm - Leukocyte Endothelial Interactions David Pritchard; Jose Lopez
Lectures: 1:30 pm - 2:20 pm - Inflammation: Is malaria a vascular disease? Atis Muehlenbachs, University of Washington
2:30 pm - 3:20 pm - Inflammation: Why do plaques rupture? - Elaine Raines, University of Washington
3:30 pm - 4:20 pm - Inflammation: Why do plaques not rupture? David Dichek, University of Washington
Breakout: 4:30 pm 5:20 pm - Lipids and Free Radicals - Jay Heinecke, Mike Rosenfeld, Karin Bornfeldt
August 6 - Regeneration of the Vessel Wall
Lectures: 8:30 am 9:20 am - Regenerative Biology: Can hearts be rebuilt? - Charles Murry, University of Washington
9:30 am 10:20 am - Regenerative Biology: How do vessels get coated? Michelle Tallquist, University of Texas Southwestern Medical Center, Dallas,
10:30 am 11:20 am - Regenerative Biology: Blocking angiogenesis - Tatiana Byzova, Cleveland Clinic
Breakout: 11:30 am 12:15 pm - Angiogenesis Roberto Nicosia, Mary Jo Mulligan-Kehoe, Tatiana Byzova, Michelle Tallquist
Lectures: 1:30 pm - 2:20 pm - Regenerative Biology: Adipose Stem Cells - Keith March, Indiana University
2:30 pm - 3:20 pm - Regenerative Biology: Ultrasound Microscopy of Blood Vessels Jonathan Lindner, Oregon Health and Science University
3:30 pm - 4:20 pm - Regenerative Biology: How to make a heart beat. - Mike LaFlamme, University of Washington
Breakout: 4:30 pm 5:20 pm - Stem Cells Morayma Reyes, Keith March, Mark Majesky
August 7 - Vasculopathies and Genetics
Lectures: 8:30 am 9:20 am - Vasculopathies: Does diabetes cause vascular diseases?- Karin Bornfeldt, University of Washington
9:30 am 10:20 am - Vasculopathies: Is intimal hyperplasia genetically determined? - Michael Reidy, University of Washington
10:30 am 11:20 am - Vasculopathies: Is aging a vascular disease? - Peter Rabinovitch, Univ of Washington
Breakout: 11:30 am 12:15 pm - Human Genetics Gail Jarvik, Gary Gibbons; Debbie Nickerson,
Lectures: 1:30 pm - 2:20 pm - Genetics: Genetical Genomics of Vascular Disease - Eric Schadt, Rosetta Inpharmatics/Merck Research Laboratories
2:30 pm - 3:20 pm - Genetics: Mining the Murine Genome for Models of Vascular Disease - Jake Lusis, University of California, Los Angeles
3:30 pm - 4:20 pm - Genetics: Mining the Human Genome for Causes of Vascular Disease - Gail Jarvik, University of Washington
Breakout: 4:30 pm 5:20 pm - Murine Genetics - Jake Lusis, Eric Schadt, Michael Chin
Evening: 6:30 pm - Informal dinner with faculty and fellows at Dakdyll
POSTERS: Fellows supported by training programs at the UW will submit posters. . Students from outside the UW are also encourages to submit posters. Awards will be made for the best work.
Scholarships: We hope to have funds for scholarships.
BREAKOUTS These late morning and late afternoon sessions will be informal discussions led by three faculty members. Each breakout will be held once in the AM and once in the PM so all students can attend.
PRE TEST : Vascular biology, like neurobiology and immunology, is a systems topic that assumes students already know the basic principles of cell biology, molecular biology, and genetics. To assist students in preparation for the course, a self administered pretest is available at www.navbo.org/Vasculata2008/Pre-SelfTest.pdf. A POST TEST: will also be made available
ON LINE LIBRARY: Faculty will be posting relevant articles to an online library available to students during the course.
PODCASTS: Lectures will be recorded as podcasts and made available to students after the course.
