Miranda Good, Ph.D.

Assistant Professor
Tufts Medical Center

Research Interests:  My laboratory’s long-term research goal is to investigate the contribution of vascular dysfunction in ischemic injuries and to the development of neurological diseases, such as ischemic stroke and Alzheimer’s Disease (AD), and to identify novel targets, such as endothelial Panx1, for therapeutic intervention. Panx1 channels are expressed throughout the vasculature but regulate distinct signaling mechanisms depending on location, such as arterial verses venous endothelial cells. I have recently found that endothelial Panx1 regulates cerebral arterial myogenic tone and venous inflammation, which are both significantly dysregulated in ischemic stroke and AD. My lab takes an interdisciplinary and collaborative approach encompassing fundamental molecular and cellular biology, in vivo state-of-the-art imaging technologies, and in vivo pathophysiological models (mouse and human) to further our understanding of how blood flow regulation and inflammation contribute to the etiology of neurological diseases.

NAVBO Activities:
Member since 2015
As the secretary of MCS was involved in meeting organization and programming for Vascular Biology 2023 and 2024
Chaired sessions regularly (e.g. IVBM 2022)

Related Experience:
2020 – 2024 Secretary, Microcirculation Society (2-year position, re-elected)
2025-2028 Awards committee, Microcirculation Society
MCS Annual Meeting organizer (as secretary of MCS) - Experimental Biology 2022