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Vasculata

Environmental Determinants of Vascular Health & Disease
Duke University
July 18-21, 2022

Organizers:
Patty Lee, M.D., Duke University
Edward Moreira Bahnson, Ph.D., University of North Carolina at Chapel Hill
Francis Miller, M.D., Wake Forest University School of Medicine

Special Thanks to 
          Nortis         

for their support of Vasculata!

Preliminary Program

Download a pdf of the program

Monday, July 18, 2022 – Day 1

7:30 AMContinental Breakfast and Registration
8:30AMWelcome
Patty J Lee, M.D., Duke University
8:40 AMKeynote: Victoria L Bautch, Ph.D., University of North Carolina at Chapel Hill – Blood Vessels and Disease: BMP Signalling
9:30 AM – 11:00 AMSession 1 – Genetic and Epigentic Modifiers in Diverse Vascular Niches
Distal lung stem cells and regeneration
- Purushothama Tata, Ph.D., Duke University
Non-cirrhotic portal hypertension: an underrecognized entity and new concept
- Xuchen Zhang, MD, Ph.D., Yale University
Transcriptional regulation of SMC phenotype in vascular development and disease
- Christopher Mack, Ph.D., University of North Carolina at Chapel Hill
11:30 AM – 1:00 PMSession 2 – Vascular Remodeling & Hypertension
Moderator: Daniel Greif, MD, Yale
The Vasculature in Pulmonary Arterial Hypertension
- Sudarshan Rajagopal, M.D., Ph.D, Duke University
RhoA signaling in the development of hypertension and vascular stiffness
- Joan Taylor, Ph.D., University of North Carolina at Chapel Hill
The vascular modeling in the lung
- Ke Yuan, Ph.D. FAHA, Boston Children’s Hospital & Harvard Medical School
1:00 PM – 2:30 PMLUNCH with a presentation on Diversity, Inclusion, Equity (DEI)
Matthew Moreira Bahnson, Ph.D and Edward Moreira Bahnson, Ph.D

3:00 PM – 5:30 PM

Workshops Group A (10-15 people each)
Workshop 1: Mass spectrometry-based proteomics: sample prep and data analysis
Workshop 2: Light Sheet Microscopy (facilitated by Miltenyi Biotec)
Workshop 3: Spatial Transcriptomics
Workshop 4: Applying 3D-Engineered Vasculature-on-Chip Models in Drug Discovery Research (facilitated by Nortis)
5:30 PMWrap-up Day 1

Tuesday, July 19, 2022 – Day 2

7:30 AMContinental Breakfast and Registration
8:30 AM – 10:30 AMSession 3 Vascular Biology and Signaling
Moderator: Daniel Greif, MD, Yale
NADPH Oxidases and Vascular Disease
- Francis Miller, M.D., Wake Forest
Respiratory vasoregulation by RBC-derived mediators in health and disease
- Tim McMahon, M.D., Ph.D., Duke University
Nrf2 activators to combat arterial disease
- Edward Moreira Bahnson, Ph.D., University of North Carolina at Chapel Hill
P450- and cyclooxygenase-derived eicosanoids in heart and vascular function
- Matt Edin, Ph.D, NIEHS
11:00 AM – 12:00 PMSession 4 - Vascular Homeostasis and Angiogenesis
Moderator: Edward Moreira Bahnson, Ph.D, UNC
Mechanisms Regulating Vascular Homeostasis
- Chris Kontos, M.D., Duke University
Smooth muscle cell pathobiology in cardiovascular disease
- Daniel Greif, M.D., Yale University
 LUNCH (on your own)
2:00 PM – 4:30 PMWorkshops Group B (10-15 people each)
Workshop 1: Mass spectrometry-based proteomics: sample prep and data analysis
Workshop 2: Light Sheet Microscopy (facilitated by Miltenyi Biotec)
Workshop 3: Spatial Transcriptomics
Workshop 4: Applying 3D-Engineered Vasculature-on-Chip Models in Drug Discovery Research (facilitated by Nortis)
5:00 PM – 6:30 PMPoster Session A
6:30 PMWrap-up Day 2

Wednesday, July 20, 2022 – Day 3

7:30 AMContinental Breakfast and Registration
8:30 AM – 10:00 AMSession 5 – Data Science and Informatics
Secretomics to interrogate mechanisms of cellular signaling
- Matt Foster, Ph.D., Duke University
Xenon MRI of lung vasculature
- Bastiaan Driehuys, Ph.D., Duke University
Functional Genomics Approach to Investigating Proximal Pulmonary Arterial Remodeling
- Ed Manning, MD, Ph.D., Yale University
10:15 AM – 11:45 AMSession 6 – Crosstalk Between Vessels, Immune Cells, & Tissues Session
Intersections between Endothelial Innate Immunity & Senescence
- Patty J Lee, M.D., Duke University
Epigenetic modifications to immune cells link smoking to atherosclerosis
- Suzanne Martos, Ph.D., NIEHS
Interactions between Bone and Microvasculature Following Ischemic Stroke
- Jacqueline Cole, Ph.D, NCSU
11:45 AM – 1:15 PMWorkshop 4 – Grant Writing Workshop (All) – Michael Gunn, M.D, Duke University
1:15 PM – 2:15 PMLUNCH (on your own)
2:15 PM - 3:15 PMSession 7 - Emerging Microbes and other Environmental Stressors
Chronic allergen exposure models of pulmonary hypertension and vascular remodeling
- Jennifer Ingram, Ph.D., Duke University
Environmental-host inflammatory responses in immune and vascular cells
- Robert Tighe, M.D., Duke University
3:15 PM – 4:30 PMPoster Session B
4:30 PM – 6:00 PMExplore Downtown Durham/Free Time
6:00 PMDinner at Tobacco Road Sports Cafe at the Durham Bulls Stadium

Thursday, July 21, 2022 – Day 4

7:30 AMContinental Breakfast and Registration
8:30 - 9:00AMKeynote – Sonia A. Rapaport M.D. - Mold, Mycotoxins, and Health
9:00 – 10:30 AMTalks from selected abstracts
9:00am – Hyperactive GNAQ mutation in endothelial cells drive aberrant vascular morphology and signaling
- Lindsay Bischoff, Cincinnati Children's Hospital Medical Center
9:15am – The role of CD44 variants in coronary vascular rarefaction and the development of left ventricular diastolic dysfunction in HFpEF
- Katie Anne Fopiano, Medical College of Georgia at Augusta University
9:30am – The role of adipose tissue identity in blood pressure regulation
- Mascha Koenen, Rockefeller University
9:45am – Endothelial lipid droplets link metabolic syndrome to blood pressure elevation
- Boa Kim, University of Pennsylvania
10:00am – The endothelial chromatin remodeling enzymes BRG1 and CHD4 transcriptionally regulate extracellular matrix production to promote lung development
- Meng Ling Wu, Oklahoma Medical Research Foundation
10:15am – Podoplanin regulates angiogenesis and lymphangiogenesis through physical recognition
- Donghyun Jeong, University of Notre Dame
10:45AMConcluding Remarks
Patty J Lee, M.D, Duke University
11:00AM
End – Have a safe trip home

 

Vasculata 2022 will take place in the Great Hall, Trent Semans Center for Health Education, 8 Searle Center Drive, Durham, NC 27710

For information about getting to and around Duke - visit this web site: https://services.duke.edu/transportation/ 

We have included a list of transportation options, restaurants and sightseeing and activities while you are in town.

If you are traveling by car, click here for parking information.

 

COVID-19 Protocols for Duke University Events


Transportation

CompanyWebsite
GoDurham TransitWebsite
LyftWebsite
Rental Cars at RDUWebsite
UberWebsite

 


Places to Eat/Drink

Food - On or Near Campus

VenueCuisineWebsiteMap
Alpaca ChickenPeruvianWebsiteMap
Blue Corn CaféLatin American FusionWebsiteMap
Burger BachNew ZealandWebsiteMap
ClocheCoffee and SnacksWebsiteMap
Cocoa CinnamonCoffee and SnacksWebsiteMap
Elmo's DinerCasual AmericanWebsiteMap
Enzo's Pizza CompanyCasual PizzaWebsiteMap
Fairview at the Washington Duke InnUpscale AmericanWebsiteMap
GRUB DurhamSouthernWebsiteMap
GuasacaVenezuelan TakeoutWebsiteMap
Happy and HaleQuick HealthyWebsiteMap
Heavenly BuffaloesQuick Casual TakeoutWebsiteMap
Itaewon GrillQuick Casual KoreanWebsiteMap
Joe Van GoghCoffee and SnacksWebsiteMap
JujuAsian FusionWebsiteMap
Lime and LemonIndianWebsiteMap
Mad HattersCasual BakeshopWebsiteMap
Metro 8 SteakhouseAmerican FusionWebsiteMap
NOSH at Jo Rae Café (Trent Semans)Casual AmericanWebsiteMap
ParizadeUpscale MediterraneanWebsiteMap
SmashburgerQuick Casual AmericanWebsiteMap
The LoopCasual AmericanWebsiteMap
Triangle Coffee HouseCoffee and SnacksWebsiteMap
Vin RougeFrenchWebsiteMap

Downtown

VenueCuisineWebsiteMap
It’s a Southern ThingSouthernWebsiteMap
Bull City Burger and BreweryCasual American BreweryWebsiteMap
Bull McCabe's Irish PubCasual IrishWebsiteMap
Counting HouseUpscale AmericanWebsiteMap
Clouds BrewingCasual AmericanWebsiteMap
Dames Chicken and WafflesCasual SouthernWebsiteMap
DashiRamen/JapaneseWebsiteMap
Dos PerrosUpscale MexicanWebsiteMap
Durham DistilleryBreweryWebsiteMap
Durham FoodhallVariousWebsiteMap
Foster Street CoffeeCoffee and SnacksWebsiteMap
Fullsteam BrewerySmall Plate BreweryWebsiteMap
Geer Street GardenAmerican FusionWebsiteMap
Gonza Tacos Y TequilaMexicanWebsiteMap
M SushiJapaneseWebsiteMap
Mateo Bar de TapasUpscale SouthernWebsiteMap
Mothers & Sons TrattoriaItalianWebsiteMap
ParlorLocal Ice CreamWebsiteMap
Pizzeria ToroWood-Fired PizzaWebsiteMap
PlumUpscale SouthernWebsiteMap
Ponysaurus Brewing CompanyBrewery/Food TrucksWebsiteMap
Pour TaproomCasual Self-Serve BarWebsiteMap
Rue ClerFrenchWebsiteMap
The Blue Note GrillCasual BBQ/MusicWebsiteMap
The PitCasual Caronlina BBQWebsiteMap
ToastCasual ItalianWebsiteMap
ViceroyIndian/FusionWebsiteMap

American Tobacco Campus

VenueCuisineWebsiteMap
Boricua SoulAfrican/CaribbeanWebsiteMap
Mellow MushroomCasual/PizzeriaWebsiteMap
Tobacco Road, DurhamCasual American Bar/GrillWebsiteMap
NanaSteakCasual American Bar/GrillWebsiteMap
Parker and OtisCasual/CafeWebsiteMap

South Durham

VenueCuisineWebsiteMap
Foster's MarketCasual GourmetWebsiteMap
GuglhupfCasual GermanWebsiteMap
Pops Backdoor PizzaUpscale PizzaWebsiteMap
Sitar Indian CuisineIndianWebsiteMap
Thai CaféCasual ThaiWebsiteMap
The Refectory CaféHealthy AmericanWebsiteMap

Sightseeing and Activities

Download a pdf

Transportation

CompanyWebsite
GoDurham TransitWebsite
LyftWebsite
Rental Cars at RDUWebsite
UberWebsite

The Lodge at Duke Medical Center

The Vasculata organizers have secured a limited number of rooms for attendees.  Please make your reservations as soon as possible and no later than June 22, 2022 (this is our group rate cut-off date). The group rate is $109 a night. The meeting will start at 8:30am on Monday, July 18, with badge pick up and breakfast beginning at 7:30am.  Please make your reservations accordingly - the room block starts on the night of July 17.

Walking Directions from The Lodge to Trent Semans

Make your Reservations:

Telephone:  
Guests may reach our hotel reservations department by dialing (919) 286-3111 and requesting Vasculata (Group ID: 19456) guest room block.

~OR~

Online:

Guests may make reservations online using the following reservation booking link:  Vasculata

*The reservations link may not be supported on all mobile devices*

Please do not hesitate to contact the "The Lodge at Duke Medical Center" at (833) 313-2165 or (919) 286-3111 if you have any questions or would like any additional information.

The hotel is located at 
2306 Elba Street
Durham, North Carolina   27705

Phone (919) 286-3111
Fax (919) 286-5115
www.lodgeatdumc.com

Directions from airport to hotel


Here is a secondary hotel.  Please note we do not have an agreement here for a group rate or a block of rooms.

University Inn at Duke University Medical Center
502 Elf St.
Durham NC 27705
(919) 286-4421
(800) 313-3585
www.UniversityInnDuke.com

Walking Directions from the University Inn to Trent Semans

Rates:
-              $109 plus tax $123.72 for a standard rm (single or 2 beds)
-              $124 plus tax $$140.74 for a suite (single or 2 beds) - Suite come with a pullout sofa, lazyboy, table with 2 chairs, a kitchen area with sink, microwave, refrigerator, iron board/iron

Directions from airport to hotel

Registration for Vasculata 2022 is NOW OPEN.  Click here.  

Regular Registration Rates (early bird ended on June 1)

Trainee (students and postdocs) members of NAVBO:  $200USD

Non-member trainees: $275USD

All undergraduate students: $100USD

NAVBO Regular Members:  $475USD

Non-members who are faculty, PIs, etc.:   $550USD

Consider joining NAVBO to save on your registration plus receive other benefits as well - https://members.navbo.org/member-application

Special notice for students - if you identify with an underrepresented group in science (Black/African American, Latinx/Hispanic, Indigenous Peoples of America/Native American, including Native Hawaiian and Alaskan, and LGBTQ+) join NAVBO for free through our Advancing Young Voices through Diversity and Inclusion Program.  Complete the membership application here:  https://members.navbo.org/ap/Membership/Application/gLWqvZpX

A number of scholarships will be available based on need and will cover at a minimum the registration and housing.

We have extended the deadline for applications to May 23.

Applications will be accepted online only through the submission form (link below) through May 23 - thank you.

Applications must include the following:

1) Responses to the four questions below. 

  • Please provide a summary of your project in layman's terms. Describe in 300 words, the disease or basic scientific question that you are investigating, the hypothesis, methods used, results and conclusions.
  • Where do you, the applicant, see yourself in five years?  Describe in 100 words. your professional goals and plans.
  • What is the main reason that we should select you for this scholarship? Describe in 100 words, any circumstances which the committee should be informed of to make their decision. 
  • How will you spend the money? Describe in 100 words, how you will use the scholarship money.  Be as specific as possible.

2) A letter from the applicant's supervisor/PI that

  • verifies your status within the lab/department (Be specific--3rd year graduate student; post doc in lab for two years, etc.)
  • confirms that there are little to no funds available for your trainee to attend Vasculata

3.) Applicant's CV

4.) Optional Abstract. It is NOT necessary to submit an abstract to qualify for the scholarship; however, it is strongly encouraged. 

ALL documents should be in pdf format.

Be sure you have all supporting documents on hand when completing this form.    You will not be able to save and return to this form.

Submit your Scholarship Application Here

Abstracts are due June 6 by 5:00pmEDT

Be sure to read the Policies and Procedures included on the Abstract Submission Site.

You'll notice the IVBM logo - we are sharing the site.  Create an account and log in, you'll then see the "Vasculata" button to proceed. 

When preparing your abstract:

  • Abstract Size and Limitations: Titles of abstracts are limited to 25 words; the abstract text is limited to 1,750 characters (this number includes spaces and punctuation).
  • Format: Do not include authors’ names and affiliations within the abstract body. The name of your company or institution will appear as it does in the database.
  • Please enter institution names exactly the same for all authors from a single institution. Please enter complete information for all co-authors including street and email addresses.
  • Do not include references, credits or grant support in your abstract; however, these should be acknowledged within your presentation.
  • Proofread abstracts carefully to avoid errors before submission. No proof pages will be sent to authors.
  • The presenter is responsible for expenses associated with the presentation of an abstract and attendance at the meeting (if you need financial assistance, apply for a scholarship).
  • Incomplete abstracts will be deleted on June 30, 2022.
  • All abstracts will be presented as Posters.

Six abstracts will be chosen to be given as short oral presentations on the last day of the meeting in addition to the poster presentation.  Authors will be notified prior to the meeting in order to have time to prepare their talk.

Topics for poster presentations are:

Angiogenesis
Atherosclerosis
Cardiovascular Disease
CNS and Cardiovascular Health
COVID-related Vascular Complications
Developmental Vascular Biology
Endothelial Cell Biology
Environmental Stressors
Genetics and Epigenetics Modifiers
Inflammation
Informatics
Lymphatics
Mechanotransduction
Organ Transplant
Stem Cells in Vascular Biology
Tissue Engineering and Regenerative Medicine
Vascular Crosstalk
Vascular Signaling
Vascular Biology – Other

Submit your abstract

Funding for this conference was made possible (in part) by 1R13HL164033 from the National Heart Lung and Blood Institute (NHLBI). The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention by trade names, commercial practices, or organizations imply endorsement by the U.S. Government.