BBHV - Basic Biology of Blood, Heart and Vasculature

The BBHV reviews a wide range of grants focused on cardiovascular disease, hematopoiesis, and vascular biology. Applications focused on basic molecular and cellular mechanisms and physiology of blood, heart and vascular cells and tissues in both normal and pathologic conditions are appropriate to submit to this study section. The applications in BBHV typically use cellular, biochemical, biophysical, immunological, genetic, pharmacological, and molecular biological approaches in in vitro and in vivo experimental models.

For more information, visit the web page: https://public.csr.nih.gov/StudySections/DTCS/IVBH/BBHV

BMBI- Biomaterials and Biointerfaces Study Section

The BMBI study section reviews applications with a focus on biologically relevant research in materials science and the interaction of material surfaces with biological systems such as cells and organoids. Areas of interest include the design, and synthesis of biomaterials; the use of biomaterials in tissue engineering; characterization of new or existing biomaterials; and the interactions of biomaterials with proteins, membranes, cells, and tissues. Many applications reviewed in this study section focus on building bioengineered blood vessel networks and vascular grafts or on building bioengineered vascularized tissues.

For more information, visit the web page: https://public.csr.nih.gov/StudySections/DBIB/BBBT/BMBI

BIND - Brain Injury and Neurovascular Disorders

The Brain Injury and Neurovascular Disorders (BIND) study section reviews applications investigating the mechanisms, pathophysiological processes, and sequelae involved in vascular, traumatic, and metabolic injury (acute and chronic) of the central nervous system (CNS), including spinal cord injury (SCI), and epilepsy. Applications reviewed by BIND include primarily human subject-based studies targeting mechanisms of brain injury, developing and testing therapeutic strategies to enhance repair and regeneration in the injured CNS, and clinical studies defining biomarkers and pathological processes and outcomes in humans. Additional approaches considered by BIND include genomic, imaging, neuropathology, neurostimulatory, behavioral, and therapeutic/screening studies.

For more information: https://public.csr.nih.gov/StudySections/DNDA/NPA/BIND

CRD - Cardiovascular and Respiratory Diseases

The Cardiovascular and Respiratory Diseases (CRD) study section reviews applications that address the etiology, determinants, distribution and outcomes of cardiovascular and respiratory phenotypes, disorders and diseases from a population health perspective. Applications reviewed will examine a range of exposures and risk factors for cardiovascular and respiratory diseases and disorders including but not limited to genetic, epigenetic, biological, biomedical and environmental risk factors. Studies reviewed in CRD have a population health focus. Applications that focus on the pathophysiology or the underlying mechanisms of these diseases and disorders especially those that primarily use animal or other experimental models are reviewed in other study sections.

For more information: https://public.csr.nih.gov/StudySections/DABP/EPH/CRD

CDD - Cardiovascular Differentiation and Development

The Cardiovascular Differentiation and Development (ZRG1 CDD 81) Special Emphasis Panel (SEP) reviews basic research applications related to development and differentiation of cardiovascular systems that include heart, vascular and lymphatics. Experimental approaches and technologies typically include, but are not limited to cellular, molecular, genetic, genomic/proteomic and use of transgenic models.

Studies utilize varied experimental model systems including mouse, chick, zebrafish, xenopus and drosophila, among others. ZRG1 CDD 81 reviews molecular and genetic studies of human cells and tissues as well as the evaluation of bioengineered cells and tissues in the context of cardiac, vascular or lymphatic systems.

• Cardiac development, including: commitment and differentiation of cardiac cell phenotypes; looping morphogenesis; cardiac chamber specification, valvulogenesis; epicardial and coronary vessel development; neural crest in developing heart and great vessels; cardiac conduction system; embryonic cell processes, cellular signaling and transcriptional regulation in heart development, structural or mechanical controls of cardiac development, normal developmental cardiac hypertrophy
• Vascular development, including: origin, commitment and differentiation of endothelial and smooth muscle cell populations; vasculogenesis and angiogenesis; patterning and organization of the vascular system; vascular remodeling in the postnatal organism; neovascularization in adults recapitulating embryonic and fetal processes.
• Lymphatic development including: differentiation, development and organization of the lymphatic vascular system; molecular and cellular mechanisms of lymphangiogenesis; lymphedema; structural and mechanical influences on lymphangiogenesis
• Stem cells: differentiation of embryonic and adult stem cells into cardiomyocytes, endothelium, smooth muscle and other components of the cardiovascular system; resident stem cells in regeneration and repair of myocardium and vasculature in vivo
• Human genetics of cardiac and vascular malformations; studies related to human congenital defects of cardiovascular system; modeling of human developmental cardiovascular diseases in different organisms.
• Evaluation of bioengineered tissue in the context of developing, differentiating or regenerating cardiac, vascular or lymphatic systems.

For more information, visit the web page: https://public.csr.nih.gov/StudySections/DTCS/RCCS/ZRG1CDD81

CFSR - Cell Fate, Stem Cells and Regeneration

Note: Starts with October 2026 Council round submission dates (Cycle I due dates).

The Cell Fate, Stem Cells, and Regeneration Study Section reviews applications covering topics in developmental and regeneration biology using diverse animal and ex vivo models, to understand the regulation of cellular specification and differentiation in embryogenesis and adulthood. Studies of embryonic, adult, and induced pluripotent stem cells, and their capacity for reprogramming, regeneration and repair are appropriate. Cell biological, biochemical, genetic, imaging and molecular approaches to address questions at the level of tissues, organs and the whole organism.

For more information: https://public.csr.nih.gov/StudySections/DBIB/CDB/CFSR

HTBT- Hemostasis, Thrombosis, Blood Cells and Transfusion

HTBT reviews applications involving basic and applied aspects of hemostasis, thrombosis, hematopoiesis, red blood cells, white blood cells, platelets, transfusion, blood rheology and hemodynamics, and endotheliopathy. Studies using cellular, biochemical, biophysical, immunological, genetic, pharmacological and molecular biological approaches to define normal and pathological processes are reviewed. Applied aspects of normal and abnormal hematopoiesis, as well as applied aspects of the formed elements of the blood are also reviewed. Additional areas of review include hematopoietic stem cells, hematopoietic growth factors and their receptors, iron and heme metabolism, blood cell cytoskeleton biology, myeloid biology, transfusion medicine and gene therapy. HTBT does not review applications related to leukemia.

For more information, visit the web page: https://public.csr.nih.gov/StudySections/DTCS/IVBH/HTBT

IVPP - Integrative Vascular Physiology and Pathology

The IVPP study section reviews applications focused on vascular and endothelial cells, blood vessels and lymphatics and their role in normal physiology and disease. Cellular, biochemical, biophysical, immunological, genetic, pharmacological, and molecular biological approaches are typical. Basic and applied aspects of cardiovascular regulation are reviewed that focus on the physiology of blood pressure regulation, the pathogenesis of hypertension, biology of the endothelium and vascular smooth muscle cells and vascular homeostasis and dysfunction in experimental models. Studies on cell surface receptors and signaling processes of various hormones, paracrines, and autocrines and their mechanisms of action as related to hypertension, humoral control of circulation, regional hemodynamics, and circulation are also considered.

For more information, visit the web page: https://public.csr.nih.gov/StudySections/DTCS/IVBH/IVPP

NVBC - Neurovascular, Blood-Brain Barrier, and Clearance Pathways

Note: Starts with October 2026 Council round submission dates (Cycle I due dates).

The NVBC Study Section reviews neuroscience applications involving cellular and molecular aspects of the blood-brain barrier (BBB), neurovascular system, and clearance pathways. The study section also reviews applications involving BBB breakdown and restoration, and therapeutic delivery and retention. Applications that study cellular and molecular aspects of the blood-brain barrier (BBB) and neurovascular system involving BBB models, BBB breakdown and restoration, and therapeutic delivery and retention are also reviewed in this review panel. Studies can be preclinical, translational or clinical in nature using relevant vertebrate and invertebrate animal models.

For more information: https://public.csr.nih.gov/StudySections/DNDA/NPA/NVBC

PVP - Pulmonary Vascular Disease and Physiology

The Pulmonary Vascular Disease and Physiology (PVP) study section reviews integrative research involving pulmonary vascular biology and disease, respiratory biophysics and biomechanics, neural control of breathing, and upper airway physiology. Methods may include molecular and cellular approaches, normal and genetically modified animal models, human subjects, and mathematical modeling. Emphasis is on physiologic, integrative, and translational approaches, including combining model simulations with experiments, interactions between and across tissues and cell types, and hierarchical approaches that link micro- and macro-level responses.

For more information: https://public.csr.nih.gov/StudySections/DTCS/IVBH/PVP

TDPS - Therapeutic Development and Preclinical Studies

Applications reviewed in TDPS will typically focus on preclinical work in animal models, where research efforts are focused on the generation/development of novel therapies within fields including cardiac and vascular systems. Proposed research may involve efforts to develop new understanding/perspectives associated with cardiac and vascular dysfunction/toxicology. Aims may focus on device optimization, therapeutic target development and drug discovery programs.

For more information: https://public.csr.nih.gov/StudySections/DTCS/RCCS/TDPS

TFO - Tissue Formation and Organogenesis

The Tissue Formation and Organogenesis Study Section focuses on cellular, molecular, and morphogenetic mechanisms that contribute to tissue and organ formation in the developing embryo. Studies of the cellular and molecular basis underlying the formation of germ-layers, gastrulation, organization of cells into tissues, cell-cell communication, adhesion, migration, impact of cellular and subcellular processes on development, force generation, and the developmental basis for birth defects are appropriate. A major emphasis is on the cardiovascular, digestive, endocrine, lymphatic, respiratory, integumentary, and urogenital systems. Studies utilize varied experimental systems including both vertebrate and invertebrate organisms and ex vivo models.

For more information: https://public.csr.nih.gov/StudySections/DBIB/CDB/TFO