Training Programs in Vascular Biology
Pathobiology Of Occlusive Vascular Disease – University of Texas Health Center, San Antonio, TX
Director and Contact:
Dr. James D. Stockand, PhD
University of Texas Health Science Center
Department of Cellular and Integrative Physiology -7756
7703 Floyd Curl Drive, MSK 7756
San Antonio, TX 78229
Program Scope and Mission – Cardiovascular disease complications remain the major leading cause of death and disability in the United States and other developed countries. While lifestyle clearly contributes to the development of cardiovascular disease, it has not proven realistic to expect resolution of major morbidities (and attenuate costs) simply on the basis of changes in lifestyle. Consequently, biomedical science must continue to address improvements in the prevention, diagnosis and treatment of the widespread and devastating complications of cardiovascular disease. To achieve this goal, a cadre of well-trained, multidisciplinary scientists, capable of working in investigative teams, is required. This postdoctoral research training program enables the continued achievement of excellence in research training in cardiovascular pathobiology by preparing new investigators with the necessary competencies and breadth of expertise needed for future biomedical research.
This is a multi-disciplinary postdoctoral research training program in cardiovascular science that annually supports six doctoral graduate fellows in medicine, dentistry, veterinary medicine, or the basic biomedical sciences. Program faculty are distributed among twelve academic departments at the University of Texas Health Science Center at San Antonio, and two departments at nearby sister institutions, the University of Texas at San Antonio and the Southwest National Primate Research Center.
Training in Botanical Approaches to Combat Metabolic Syndrome - Pennington Biomedical Research Center
Director and Contact:
Phillip J. Brantley, PhD
Associate Executive Director For Scientific Education
Pennington Biomedical Research Center/LSU
6400 Perkins Road
Baton Rouge, Louisiana 70808-4124
Program Scope and Mission – Pennington Biomedical Research Center in Baton Rouge, Louisiana invites applications for postdoctoral fellowships on their NCCIH Institutional Training. We are seeking MDs or PhDs with biomedical research experience who are interested in conducting basic research into obesity, diabetes, and the use of botanicals to attenuate metabolic syndrome. Eligible Applicants must be a US citizen or green card holder. Evidence of motivation and skills in scientific writing such as publications and grant experience are highly desirable. Fellowships provide up to three years of funding, and include didactic instruction and mentored laboratory based training necessary to establish an independent research career. http://www.pbrc.edu/training-and-education/postdocs/botanical-approaches-to-combat-metabolic-syndrome/
T32 Kidney Disease and Inflammation - University of Virginia
Director and Contact:
Mark D. Okusa, MD
1300 Jefferson Park Avenue
West Complex, Room 5097B
University of Virginia Health System
Charlottesville, VA 22908–0133
Program Scope and Mission – Kidney disease is a major health problem for both adults and children. Renal diseases of various etiologies continue to grow at a rate of epidemic proportions. Furthermore there is a diminishing “pipeline” of nephrology trainees leading to a lack of new discoveries, cures and clinical trials in the kidney research arena. It is imperative that we meet this challenge and ensure the training of a new cadre of outstanding investigators in kidney-related research. The goals of the program are to identify promising candidates and train them for careers in academic nephrology. We have assembled an exemplary team of clinician and basic science investigators with an outstanding track record of mentorship from various Departments and Centers including: Medicine, Pediatrics, the Pediatric Center of Excellence in Nephrology, Pharmacology, Microbiology, Molecular Physiology and Biophysics, Biomedical Engineering, the Cardiovascular Research Center, Surgery, the Beirne Carter Center of Immunology and Public Health Sciences. The basic/translational faculty laboratories offer research experience that links kidney development, cell fate, and disease with inflammation. The program provides training and didactic instruction in fundamental and cutting-edge methodologies, including novel molecular, cellular, transgenic and imaging technologies, as well as immunology, functional genomics and novel imaging technologies. The patient- oriented clinical research program provides training in clinical investigation, epidemiology, biostatistics and human genetics. Three new mentors in genetic susceptibility to kidney disease and disease progression have been recruited. Adult and Pediatric Nephrology trainees with M.D. degrees will pursue a program consisting of 1 year of clinical training, which is not supported by the grant, and 2-3 years of research training funded by this application. PhD applicants will be required to have prior research experience and outstanding references. Each of the thirty-four mentors/co-mentors has a track record of mentorship and is an expert in one or more core areas that pertain to kidney development and disease and inflammation including: kidney development and disease pathogenesis, diabetes/vascular disease, cell signaling, leukocyte biology and patient-oriented research/genetic epidemiology. All trainees will be required to attend regular seminars, journal clubs and specific courses addressing research methodologies, experimental design, research integrity, ethics and faculty development, in addition to. Newly designed translational programs are aimed to link clinical disease with basic science. They will be expected to design, conduct, and analyze experiments with progressive independence in our new, modern, and well-equipped laboratories. We value and encourage applicants from diverse academic and ethnic backgrounds. It is the goal of the mentored training program that its graduates attain a strong foundation in translational biomedical research and be among a new generation of academic nephrologists and renal investigators who will make significant contributions in addressing the growing problem of kidney disease in the adult and pediatric populations.
Vanderbilt Clinical Pharmacology Fellowship Program - Nashville, TN
Fellowship Program Director, C. Michael Stein
Program Scope and Mission – The Division of Clinical Pharmacology at Vanderbilt offers an outstanding research-based, postgraduate fellowship program committed to training future leaders. The primary activity of trainees is research training in a mentored setting on questions relevant to drug action in man. Research can vary from bench-based translational work to clinical studies. Areas of focus include pharmacogenetics, autonomic regulation of blood pressure, vascular biology, hypertension, inflammation, arrhythmia, bone biology, oxidative stress and eicosanoids. Our T32 program requires that applicants be US citizens or permanent residents and have a clinical degree (e.g., MD or Pharm D).
Cardiovascular Research Training Program - University of Virginia, Charlottesville
Programs Administrator/Administrative Generalist
Robert M. Berne Cardiovascular Research Center
415 Lane Road (MR5) PO Box 801394
Charlottesville, Va. 22908
Program Scope and Mission – Despite decades of research there are still fundamental gaps in our knowledge of the underlying mechanisms that contribute to development and progression of most cardiovascular diseases (CVD), as well as the end stage clinical consequences of these diseases and how to better treat or prevent them. Indeed, CVD remains the leading cause of death worldwide. A central premise of our NIH T32 cardiovascular (CV) research training program (CVTP) is that these diseases are extremely complex, and that rigorous study of them requires trainees to have a strong foundation of knowledge of basic CV physiology, developmental biology, genetics, genomics, bioinformatics, epigenetics, pathology, systems biology, biomedical engineering, and many other disciplines. A major strength of our CVTP is that we have >50 outstanding clinical, translational, and basic science mentors representing all of these areas, and we have built a unique training program over the past three decades that integrates mentoring talents into producing the best trained cardiovascular scientists possible. Our goal is to provide pre-doctoral and post-doctoral trainees the necessary knowledge, intellectual capabilities, technical skills, and problem-solving abilities to conduct outstanding state-of-the-art CV research employing a wide range of powerful and innovative approaches.
The program is led by Dr. Gary K. Owens and two talented Associate Directors Drs. Brant Isakson and Shayn Peirce-Cottler who are exceptional CV researchers and mentors. Pre-doctoral trainees are selected from a large pool of outstanding trainees initially recruited into an umbrella biomedical sciences (BIMS) graduate program http://bims.virginia.edu/ or the UVA MD/PhD (NIH MST) Program https://mstp.med.virginia.edu/, whereas post-doctoral candidates are largely recruited by individual mentor labs or from one of several clinical residency-fellowship programs. After completing a highly innovative BIMS 6000 core course in integrated biology in year 01, CVTP pre-doctoral trainees take elective modular courses that are customized based on their interests and degree program. They also complete three lab rotations to aid in selection of a mentor. Only trainees who have already selected a CVTP mentor are eligible for appointment to our NIH T32 training grant. All trainees are required to take our signature CVTP advanced courses including BIMS 8052-3 (Advanced Vascular Biology) and BIMS 8064 (a trainee-run Careers/Professionalism Course), and are also required to attend our weekly research seminars, monthly research in progress sessions, bi-annual research retreats, and to complete biomedical ethics training. The CVTP also has an exceptional grant writing program including an annual workshop and approximately 20 annual grant brewing sessions.
There are many indices of the success of this program including CVTG trainees: 1) publishing many high impact first author papers including in some of the highest rated biomedical journals such as Nature, Nature Medicine, and Circulation Research; 2) having a >50% success rate in securing extramural fellowships upon first submission; 3) securing high quality post-doctoral, or faculty/leadership positions, at major academic medical centers, in the pharmaceutical industry, or with biotechnology companies; and 4) making extraordinary contributions advancing our understanding of the cardiovascular system, as well as developing better ways to treat or prevent CVD.
Pharmacology and Nutritional Sciences: Multidisciplinary Approaches for Metabolic Disease - University of Kentucky
Nancy R Webb, PhD
T32 Program Director
Department of Pharmacology and Nutritional Sciences
Director, Division of Nutritional Sciences
535 Wethington Health Sciences Building
Lexington, KY 40536-0200
Phone: (859) 218-1385
Program Scope and Mission – An NIH-funded T32 training grant entitled “Pharmacology and Nutritional Sciences: Multidisciplinary Approaches for Metabolic Disease” is housed in the Department of Pharmacology and Nutritional Sciences, Division of Nutritional Sciences at the University of Kentucky. The training grant seeks to prepare biomedical scientists for academic careers in research focused on pharmacological and nutritional approaches to prevent and treat metabolic-based disorders. The training faculty come from 8 different departments in 4 Colleges across the University of Kentucky campus. They have expertise in the four theme areas of the training grant: obesity/diabetes, cardiovascular disease, cancer, and neuroscience/aging.
Cardiovascular Disease Epidemiology Training Program - Wake Forest University School of Medicine
Randi Sullivan, MD, MHS
Wake Forest University School of Medicine
Department of Internal Medicine
Section on Cardiovascular Medicine
Medical Center Boulevard
Winston-Salem, NC 27157
Program Scope and Mission – The purpose of the CVD Epidemiology Training Program, a federally-funded National Research Service Award (NRSA) Institutional Research Training Grant (2 T32 HL076132), is to attract and train a cohort of outstanding physician scientists who will be fluent in the latest developments in cardiovascular disease and able to apply this knowledge to the conduct of new cardiovascular epidemiology and clinical cardiovascular research. Key features of the training program include completion of a Master’s Degree in Clinical and Population Translational Science with a curriculum that also includes formal training in molecular biology and genetics, supplemental training in genomics, proteomics and informatics, joint mentorship with both clinical and basic science faculty, and participation in external NHLBI sponsored short courses in cardiovascular epidemiology, and the genetics of complex heart, lung, and blood disorders.
Predoctoral Training Program in Integrative Vascular Biology - University of North Carolina - McAllister Heart Institute
Christopher Mack, Director
Associate Professor of Pathology
University of North Carolina
Chapel Hill, NC 27599
Program Scope and Mission – In response to the demands of the post-genomic era, we established the Integrative Vascular Biology (IVB) Pre-doctoral Training Program at the University of North Carolina in 2002 to promote a collaborative interdisciplinary training environment for pre-doctoral students in the cardiovascular field. The IVB Program was founded on the breadth and depth of the cardiovascular research faculty at UNC and institutional strengths in genetic model systems, state of the art cell biology and imaging, high throughput genomic and proteomic analyses, and computational biology. The overall goal of the IVB Program is to provide Trainees with the interdisciplinary and collaborative skills necessary to extend their thesis work into new, innovative, and productive directions. Our primary training faculty are drawn from 12 UNC departments and have specific expertise in heart and blood vessel development, thrombosis and hemostasis, the mechanisms that contribute to atherosclerosis, and the pathophysiology and treatment of myocardial ischemic disease. By requiring trainees to collaborate with secondary mentors outside of their Field, Department, and/or Institution, the program teaches students to apply molecular, cellular, genetic, and computational approaches to pathological and physiological questions in cell, organ, and whole animal systems; to merge hypothesis- and discovery-based research; to develop high-throughput approaches in cardiovascular models, and to translate their work to clinical settings. Trainees are exposed to the latest concepts in cardiovascular biology by enrolling in advanced paper-based courses specifically designed for UNC's Graduate Certificate Program In Cardiovascular Science, by attending formal cardiovascular seminars by inside and outside speakers, and by participating in a bi-weekly student-led discussion group. To enhance the skills necessary for effective collaboration and career advancement, Trainees attend program workshops on grant writing, career development, and scientific rigor and responsibility, and they present their data formally at the annual IVB Research Symposium, a trainee-organized event that draws over 120 cardiovascular researchers from the greater Chapel Hill area. In summary, with an outstanding history in cardiovascular research, a strong, well-funded group of investigators centered around the McAllister Heart Institute, a structured academic program in Cardiovascular Science, and institutional excellence in genetic model systems, cell biology, high throughput sequencing, and computational biology, the UNC Integrative Vascular Biology Program offers an outstanding environment for multidisciplinary training of pre-doctoral students. For more information, please contact program Director Christopher Mack.
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