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Sebastien Bonnet, Steeve Provencher, and Philippe Pibarot

May 1, 2012

The Pulmonary Hypertension Research Group
Laval University
Institute of Cardiology and Pulmonology, Quebec City


Sylvie Martin, Anne-Sophie Neyron, Vanessa Turcotte, Vincent Mainguy, Jolyane Meloche, Dr Steeve Provencher, Simon Malenfant, Dr Geneviève Dion, Dr Sébastien Bonnet, Jacinthe Poirier, Audrey Courboulin, Dr Sébastien Renard, Luce Bouchard, Ève Tremblay, Sandra Breuils-Bonnet, Marjorie Barrier.

Primary Research:
The Pulmonary Hypertension Research Group is a collaboration of clinicians and researchers working together to reveal the pathogenesis of PH, identify the mechanisms of the disease, and develop new therapeutic approaches in order to improve the care of patients with PH. Research projects and clinical studies within the institution include:

The role of microRNA in the pathogenesis of arterial hypertension

The Role of DNA damage in the etiology of PH

The metabolic basis of arterial hypertension

The Physiology of exercise among patients with PAH

Peripheral angiogenesis defects in PAH

Visit the lab's web site:

Recent Publications:

Courboulin A, Barrier M, Perreault T, Bonnet P, Tremblay VL, Paulin R, Tremblay E, Lambert C, Jacob MH, Bonnet SN, Provencher S, Bonnet S. Plumbagin reverses proliferation and resistance to apoptosis in experimental PAH. Eur Respir J. 2012 Apr 10. [Epub ahead of print]Barrier M, Meloche J, Jacob MH, Courboulin A, Provencher S, Bonnet S. Today's and tomorrow's imaging and circulating biomarkers for pulmonary arterial hypertension. Cell Mol Life Sci. 2012 Mar 25. [Epub ahead of print]

Members of the laboratory:

The Co-Investigators - Clinical investigators:

  • Geneviève Dion
  • François Maltais
  • Simon Martel
  • Mathieu Simon

The research coordinators:

In clinical research

  • Luce Bouffard
  • Jacinthe Poirier
  • Sylvie Martin

In the laboratory

  • Sandra Breuils-Bonnet
  • Ève Tremblay
  • Caroline Lambert

The students:

Post doctoral's degree

  • Sébastien Renard

Doctoral degree

  • Audrey Courboulin
  • Marjorie Barrier
  • Vincent Mainguy
  • Guillaume Margaillan
  • Jolyane Meloche
  • François Potus

Master's degree

  • Simon Malenfant
  • Anne-Sophie Neyron
  • Jérémy Loehr

Bachelor's degree

  • Anthony Courchesne