Corinne Nielsen, Ph.D.

Department of Biological Sciences
Ohio University
Athens, OH

Primary Research:

Our lab’s long-term goal is to understand how the nervous and vascular systems influence one another. We are particularly interested in determining molecular and cellular mechanisms that regulate neurovascular development and function – and mechanisms involved in neurovascular pathogenesis.

Lab Web Site: https://www.ohio.edu/cas/biosci/contact/profiles.cfm?profile=nielsenc

Members of the laboratory:

Shruthi Kandalai (undergraduate student)
Samantha Selhorst (undergraduate student)
Brittney Ward (undergraduate student)
Subhodip Adhicary (graduate student)

Recent Publications:

• Cuervo, H., Nielsen, C.M., Simonetto, D.A., Ferrell, L., Shah, V.H. and Wang, R.A. 2016. Endothelial Notch signaling is essential to prevent hepatic vascular malformation in mice. Hepatology 64(4):1302-1316.
• Nielsen, C.M., Huang, L., Murphy, P.A., Lawton, M.T. and Wang, R.A. 2016. Mouse models of cerebral arteriovenous malformations. Stroke 47:293-300.
• Murphy, P.A., Kim, T.N., Huang, L., Nielsen, C.M., Lawton, M.T., Adams, R.H., Schaffer, C.B. and Wang, R.A. 2014. Constitutively active Notch4 elicits brain arteriovenous malformations through enlargement of capillary-like vessels. Proceedings of the National Academy of Sciences USA 111:18007-18012.
• Nielsen, C.M., Cuervo, H., Ding, V.W., Kong, Y., Huang, E.J. and Wang, R.A. 2014. Deletion of Rbpj from postnatal endothelium leads to abnormal arteriovenous shunting in mice. Development 141:3782-3792.